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Research Project: EFESYS

  Efficient and Flexible Parallel and Distributed Discrete Event Simulators for Cell-Biological Systems

Abstract: The goal of the collaborative project of the University of Rostock and the Georgia Institute of Technology is to develop efficient and flexible discrete event simulation methods for cell-biological systems. The focus of the project will be on parallel optimistic approaches and the utilization of grid technology for execution. The project will built on existing and ongoing work on designing component-based, flexible simulators, multi-level, modeling and simulation in Systems Biology and on efficient, parallel, distributed simulation of large scale systems, and grid technology.

  Research Project Information
Runtime: Jan 01, 2006 until Dec 31, 2007
Project coordination: Prof. Dr. rer. nat. habil. Adelinde M. Uhrmacher ; Prof. Dr. Richard Fujimoto
Contractor(s): DAAD

One goal of this project is to develop methods enabling the realization of efficient, flexible, parallel discrete-event simulation frameworks that can be applied to cell-biological models.  Expanding upon this work we will utilize grid technology to execute the models.  The modeling formalisms that shall be supported are Devs-like variants that underlie the simulation system James-II and support a state-based view of cellular systems as well as variable structures. However, transferring the results to other modeling formalisms shall be examined as well. The methods shall be evaluated based on existing cell biological models, that have already been used for testing the performance of other simulation systems. In addition further models will be available for performance testing: which are currently under development at the University of Rostock. This project will establish a collaborative effort between the University of Rostock, i.e. the Modeling and Simulation group, and the Georgia Institute of Technology, i.e. the group lead by Richard Fujimoto, to leverage existing efforts among these institutions in these area, and create new synergies.  Specifically, this project will bring together researchers in modeling and simulation, systems biology, parallel and distributed simulation, and grid computing.

Being being part of the  DAAD PPP USA program the exchange of young scientists between both partner institutes will be supported.